Heart Disease Allegedly Linked to Higher Urinary Concentrations of BPA

A recent study has claimed that “higher urinary concentrations of bisphenol A [BPA] are associated with an increased prevalence of coronary heart disease.” David Melzer, et al., “Association of Urinary Bisphenol A Concentration with Heart Disease: Evidence from NHANES 2003/06,” PLoS ONE, January 2010. Using data from the National Health and Nutrition Examination Survey (NHANES) 2003/04 and 2005/06, researchers examined the urinary BPA concentrations of participants aged 18-74 years, “representative of the general adult population of the United States.” According to the authors, “Associations have previously been reported between urinary BPA concentrations and heart disease, diabetes and liver enzymes in adults participants of [NHANES] 2003/04.”

The 2005/06 NHANES data purportedly confirmed that “higher BPA exposure, reflected in higher urinary concentrations of BPA, is consistently associated with reported heart disease in the general adult population of the USA.” The study noted, however, that “Associations between urinary BPA concentrations and diabetes or liver enzyme increases were not statistically significant.” In addition, participants’ urinary BPA concentrations in 2005/06 were “substantially lower” than in 2003/04. The authors recommended further study “to clarify the mechanisms explaining the statistical association between BPA and adult morbidity.” See ScienceNews, January 13, 2009.